Chelsea Handler and John Mayer Headline Children's Institute Gala

The gala celebrates the enduring legacy of Michele and Rob Reiner, whose civic contributions helped launch First 5 California and influenced the national movement for marriage equality. Martine Singer, CEO of the Children's Institute, described the couple as a significant force in American civic life. The organization provides mental health services and early childhood education to roughly 30,000 families in Los Angeles County annually.

Jamie Lee Curtis receives the night's top honor for her philanthropic work, including her My Hand In Yours initiative, which has contributed nearly $2 million to Children's Hospital Los Angeles. Jake Reiner will present the award to the actor and author of 14 children’s books. John Mayer, who was named The Hollywood Reporter’s Philanthropist of the Year in 2026 for his veteran-focused foundation Heart and Armor, will perform at the event to support these ongoing community programs.